Friday, 20 January 2017

ATP Measurement in the Last Rinse Water of Automated Washer-Disinfectors



Cleaning and disinfection are essential steps in the reprocessing of medical devices. AutomatedWasher-Disinfectors (AWDs) are widely used in healthcare settings to obtain both clean and disinfected medical devices. 

ATP Measurement

The use of AWD is advocated in literature and in standards for minimizing processing variability and infective risk for the staff of the central sterile supply department (CSSD). According to the European Medical Devices Directive 93/42/EEC and subsequent amendments by 2007/47/EC a claim made on a product or procedure has to be proven.  Read more>>>>>>>>>>>>>>

Thursday, 19 January 2017

Disseminated BCG Disease in an Infant with Severe Combined Immunodeficiency

BCG (Bacillus Calmette Guerin) being a live attenuated vaccine may cause disseminated disease (BCGiosis) in patients with impaired immunity. Patients with severe combined immunodeficiency (SCID) having defection both cellular and humoral immunity are predisposed to a host of live vaccine related complications, especially BCG.

journal of infectious diseases in developing countries
We report a 6 month-old baby boy with fever for 5 months, generalized rash for 3 months, cough and cold for 1 month, poor feeding and weight loss over last 1 month. He had an uneventful perinatal period and received BCG at birth. Examination revealed mild pallor, generalized erythematous papular rash with central crusting and splenohepatomegaly. Skin biopsy and culture confirmed BCG infection while computed tomography of abdomen and skeletal survey showed disseminated involvement. Immunological investigations were suggestive of an underlying SCID. The infant showed improvement with antitubercular therapy combined with intravenous immunoglobulin and other supportive measures.

Wednesday, 18 January 2017

Candida Albicans Involvement in Denture-Related Stomatitis: A Serious and Real Clinical Concern



Colonization of oral surfaces by Candida spp. is considered a risk factor for invasive fungal infections. Oropharyngeal candidiasis manifests clinically as acute pseudomembranous, acute atrophic, chronic atrophic, chronic hypertrophic/hyperplastic and angular cheilitis.

Denture-Related Stomatitis


Denture-related stomatitis (or chronic atrophic candidiasis) is characterized by an inflammation of the mucous membrane located beneath the prosthesis, particularly under the upper denture, sometimes accompanied by hemorrhagic petechiae. Denture stomatitis is the commonest form of oral candidiasis and its reported prevalence varies widely reaching up to 65% of denture wearers. Patients may complain of a burning sensation, irritation, discomfort, bad taste and disturbance of salivation, but in the majority of cases they are unaware of the problem.  Read more>>>>>>>>>>>>>>>

Tuesday, 17 January 2017

Is Work Disability More Common among Same-sex than Different-sex Married People?



Research has repeatedly shown that lesbian, gay, and bisexual (LGB) individuals experience higher risk for both somatic and psychiatric diseases, as compared to heterosexual individuals. 

Same-sex

In addition, it has been demonstrated that LGB individuals constitute a higher-risk group for health risk behaviors such as smoking, elevated levels of alcohol consumption and substance abuse, as well as higher body-mass index among women . Also, there are some results of higher disability rates among sexual minority individuals, which is consistent with pernicious effects of minority stress. However, the prior studies are based on self reported data and their findings should hence be interpreted in the context of possible misclassifications and recall biases.  Read more>>>>>>>>>>>>>

Monday, 16 January 2017

Asthma in HIV-Infected Population: A Review of Respiratory Symptoms, Pulmonary Function Abnormalities and Pathophysiology



Several studies have investigated prevalence of respiratory symptoms in the HIV-infected population. Before anti-retroviraltherapy (ART), there was a high prevalence of dyspnea and cough in this population. 

Asthma in HIV-Infected Population


These studies showed low CD4 cell counts, history of smoking and intravenous drug use, and previous history of pneumonia were associated with increased risk of dyspnea and cough symptoms. More recent studies in the post-ART era show that respiratory symptoms continue to be common in HIV-infected individuals, with the prevalence of cough ranging from 23-37% and prevalence of dyspnea ranging from 16-44%. Read more>>>>>>>>>>>>>>

Thursday, 12 January 2017

Urinary Tract Infections in Older People with Long-Term Indwelling Catheters



Catheter-associated urinary tract infection (CA-UTI) is a relatively common infection, especially among older people with long-term indwelling urethral catheter. The term CA-UTI is used to refer to symptomatic urinary tract infection in individuals with indwelling catheter. 

Urinary Tract Infections
In general, less than 30 days with an indwelling urinary catheter is considered short term while 30 days or more is deemed as long term or chronic. Older people with chronic indwelling catheters have significantly increased risk of morbidity from CA-UTI compared to those with bacteriuria without long-term catheters. In long-term-care facilities, an estimated 5-10% of residents require chronic indwelling catheters. Indwelling catheters are used more commonly in men than in women living in these facilities, with urinary retention being the most common reason. Read more>>>>>>>>>>>>>>>