Monday, 12 September 2016

Review on Ebola Virus Disease: Its Outbreak and Current Status

Ebola virus disease (formerly called Ebola Hemorrhagic Fever) is a severe, often fatal, disease in humans and nonhuman primates, which is caused by the Ebola virus. Between 1976 and 2014 twenty-four epidemics of Ebola virus disease (EVD) were verified, mostly caused by Zaire Ebola virus (ZEBOV) in Equatorial Africa. Most outbreaks have been small, but the virus captured the attention of the world due to death rates that can be as high as 90% as well as the visceral manner in which it kills.

Ebola Virus DiseaseIn March 2014, World Health Organization (WHO) reported a major Ebola outbreak in Guinea, Liberia and Sierra Leone, western African nations. The 2014 EVD outbreak in West Africa caused by ZEBOV is the longest,largest, deadliest, and the most complex in history. As of 11 February 2015, there were 22,859 EVD cases and a total of 9,162 deaths. Compared to the cumulative sum of past episodes in 36 years (1976-2012), 2,232 infected people and 1,503 deaths there are now over ten times the total number infection cases and over six times the total number of fatalities. The Ebola virus disease outbreak in West Africa affected impoverished post-conflict countries with weak health systems and no experience with Ebola.
Ebola is a public health nightmare because it can be contacted relatively easily (especially in a hospital setting where proper precautions are not taken) and is almost always fatal. EVD can be transmitted between humans through direct contact with bodily fluids (e.g., blood, sweat) from an infected person or contaminated objects. Whereas aerosol infection has not been reported clinically, despite it has been demonstrated in experimental infection in monkeys. Read more...........

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