Andrographis paniculata, leaf extract possess antimicrobial
activity against in vitro P. falciparum culture and P. berghei in vivo.
Andrographolide is a primary bioactive compound present in Andrographis
paniculata that possess antimicrobial activity. In addition Andrographolide will protect liver, renal injuries induced by P. berghei infection, Control
blood glucose levels, prevents body weight loss and hemolysis induced by
malaria infection.
The secondary metabolites of Andrographis paniculata,
possess pharmacological activities such as anti-hemolysis, anti-malarial,
hepatoprotective, nephroprotective etc.. These
finding adds important information to the area 1 of malaria research, which
always is in need of alternative antimalarial drugs to combat the malaria,
especially drug resistant parasites. Even though it is premature to conclude at
this time that A. paniculata can be used as effective antimalarial, these
finding provides a foundation for further exploration of new effective
medicinal extracts for protection and treatment from the development of
resistance among malaria parasites. Read more>>>>>>>>>>>>>>>
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