Hepatitis D virus (HDV) is a defective
hepatotropic virus that affects only patients with hepatitis B virus (HBV)
infection. These 2 viruses share the same routes of transmission (parenteral,
sexual, and mother to child). HDV antigen was first detected in hepatocytes of HBV-infected patients with HBc antigen expression but distinct from the latter.
The more severe prognosis of HDV infection in the setting of human
immunodeficience virus (HIV) coinfection seems questionable today, even if HDV
infection is observed in 12% of HIVcoinfected patients compared to 4% in
HBV-monoinfected patients, which come from high or moderate endemic areas for
majority. Interferon treatment is less efficient in HDV infection than in HBV
infection with only 25% of sustained virological response and more than 50% of
relapse after discontinuation of therapy. Read more>>>>>>>>>>>>>>>
No comments:
Post a Comment