Sunday, 30 July 2017

Global Strategies for Elimination of Leprosy: A Review of Current Progress

There has been a global reduction in cases of leprosy over the past twenty-years due to the combined efforts of WHO, local governments, health professionals, and non-governmental organizations. Nonetheless, the number of cases remains relatively high. 

Leprosy
Leprosy
Data compiled by WHO indicates that approximately 182, 000 people, mainly in Asia and Africa, were affected with the disease at the beginning of 2012, with approximately 219, 000 new cases reported during 2011. These numbers represent significant reductions from the 5 million cases estimated during 1985 and the estimated 3 million cases in 1995. Read More>>>>>

Thursday, 27 July 2017

Elderly People with Chronic Diseases: A Vision Of The Future

The Spanish Constitution in its article 43 establishes the Right to Health and its development, through the General Health Law, urges the Sistema Nacional de Salud (SNS) and los Servicios Sanitarios de las Comunidades Autónomas (CCAA) to develop Comprehensive Plans or Autonomic Health Plans. 

Chronic Diseases
Chronic Diseases
In 2003, the Law was approved (16/2003) on Cohesion and Quality of SNS, that recommends the elaboration of Comprehensive Health Plans for the most prevalent, relevant or special pathologies involving a socio-family burden, guaranteeing comprehensive health care that includes prevention, diagnosis, treatment and rehabilitation. Read More>>>

Tuesday, 25 July 2017

The Analysis of Yellow Fever Virus Antigen in Human Serum from Epidemic Areas of Tianjin Port, 2012

Yellow fever (YF) is an acute infectious disease caused by yellow fever virus (YFV), which is one of the three infectious diseases of international health regulations. YFV belongs to flavivirus, transmitted through the medium of mosquito among vertebrates. 

Yellow Fever
Yellow Fever
As molecular epidemiological data shown, YFV has seven genotypes distribution geographically and it associates with a specific genotype in one outbreak. YFV infection has Jungle type and city type. The type of the jungle is transmitted in the form of monkey-mosquito-monkey. However, human is the main source of city type. The main clinical symptoms are fever, jaundice, hemorrhage and proteinuria, 5% to 20% of patients manifested clinical symptoms, a small number of patients came to severe case and death. Read More>>>>>

Tuesday, 18 July 2017

Retrospective-Prospective Study on Efficacy & Safety of Entecavir in Chronic Hepatitis B

Hepatitis B virus (HBV) is a partially double spiral type DNA virus. Globally, approximately over 400 million individuals are infected with hepatitis B. HBV is known as one of the most important carcinogens. 
 
Hepatitis B virus (HBV)
Hepatitis B virus (HBV)
Every year, over one million individuals die due to HBV-related causes. The retrospective part of this study with a relatively small number of studied patients could be limitations in such a study, but being a real life data of West Asian, with HBV genotype D has its weight, adding to our daily practical knowledge and experience. Read More>>>>>>>

Monday, 17 July 2017

Whole Genome Sequencing for Detection of Zoonotic Tuberculosis in Queretaro, Mexico

Tuberculosis (TB) is a disease that affects both humans and animals. Humans are predominantly infected by Mycobacterium tuberculosis whereas animals by M. bovis; however, both are susceptible to both species, with no significant clinical, radiological or pathological differences. 

Species of Mycobacterium

Mycobacterium tuberculosis and M. bovis are 99.9% similar at the nucleotide and 16S rRNA sequences, virtually identical M. bovis has usually neglected as an important pathogen in human tuberculosis; nevertheless, different studies in different populations have shown that M. bovis has an important role in human tuberculosis. In past decades, retrospective studies on stored samples reported that TB due to M. bovis is between 8 and 10%. Read More>>>>>>>>>>>

Tuesday, 11 July 2017

Prevalence and Clinical Significance of Mycoplasma genitalium in Gynecologic Patients

Although Mycoplasma genitalium is well documented as a causative pathogen in non-gonococcal, non-chlamydial urethritis in men; the manifestations of infection in women are less well described. There is now evidence suggesting it causes cervicitis and pelvic inflammatory disease (PID) in women. One of the major limitations encountered in the study of M. genitalium is that it is fastidious and difficult to culture. 

Mycoplasma genitalium
Mycoplasma genitalium
Although there is no U.S food and drug administration (FDA) approved commercial detection system, the availability of molecular methods for research and commercial purposes has altered our ability to derive valid information about the pathogenicity of this bacterium. There have been more studies in recent years researching into its pathogenicity and treatment.  Read More>>>>>>