Whole Genome Sequencing for Detection of Zoonotic Tuberculosis in Queretaro, Mexico

Tuberculosis (TB) is a disease that affects both humans and animals. Humans are predominantly infected by Mycobacterium tuberculosis whereas animals by M. bovis; however, both are susceptible to both species, with no significant clinical, radiological or pathological differences. 

Mycobacterium tuberculosis and M. bovis are 99.9% similar at the nucleotide and 16S rRNA sequences, virtually identical M. bovis has usually neglected as an important pathogen in human tuberculosis; nevertheless, different studies in different populations have shown that M. bovis has an important role in human tuberculosis. In past decades, retrospective studies on stored samples reported that TB due to M. bovis is between 8 and 10%. Read More>>>>>>>>>>>