Friday, 23 December 2016

Candida Albicans Involvement in Denture-Related Stomatitis: A Serious and Real Clinical Concern



Colonization of oral surfaces by Candida spp. is considered a risk factor for invasive fungal infections. Oropharyngeal candidiasis manifests clinically as acute pseudomembranous, acute atrophic, chronic atrophic, chronic hypertrophic/hyperplastic and angular cheilitis. Yeast-like microorganisms belonging to the Candida genus are the etiological agents of candidiasis, which are common dwellers of the oral cavity, gastrointestinal tract and vagina of normal people. However, when the conditions become appropriate, the nonpathogenic yeast forms are transformed into pathogenic invasive forms. 

Denture-Related Stomatitis

Many predisposing factors have been implicated in the development and severity of denture stomatitis, including: patient age and gender, trauma caused by the denture itself, poor oral and denture hygiene, continuous denture wear, age of denture, availability of sugar in the oral environment through dietary intake, malnourishment, smoking, alcohol consumption, impaired salivary flow and salivary gland function, diabetes mellitus, antibacterial drug therapy, corticosteroids, radiotherapy, malignancy and other immunocompromised conditions, especially acquired immunodeficiency syndrome. Read more>>>>>>>>>>>>>

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