Wednesday, 21 December 2016

Risk Factors Associated with Clostridium difficile Infection in A Pediatric Hematology-Oncology Ward

Currently clostridium difficile infection (CDI) is recognized as an increasingly important pathogen in children with increasing incidence among pediatric patients. In this study, we report the first outbreak of CDI in pediatric hematology-oncology ward in Saudi Arabia and describe the associated risk factors for CDI. This is a descriptive, epidemiologic hospital based case-control study of pediatric Patients in hematology-oncology ward who had CDI in an outbreak from January2012 to June 2013 at a tertiary hospital in Saudi Arabia, matched randomly to a control group who were admitted in the same ward during the study period. 

Clostridium difficile Infection


The main outcome measure was the adjusted odds ratio estimates of potential risk factors for CDI infection. Risk factors associated with CDI were antibiotic use with cotrimoxazole being the most used one, and length of hospital stay. Controls were found to have been treated more with penicillins and aminoglycosides. Factors associated with CDI infection are often complex and maybe confounded by local variables, antibiotic exposure and lengthy hospital stays are among many risk factors for CDI in high -risk populations.  Read more>>>>>>>>>>

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