Traditional
microbiology focused on clonal cultures of single microorganism. However, it is
now well established that majority of the microbes existing in the world couldnot be laboratory cultivated while playing essential roles in human life.
Therefore, the newly emerged metagenomic method poses an important approach to
explore the fantastic world of unculturable microorganisms.
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| Metagenomics |
With the power of
modern genomic techniques the metagenomic approach directly analyze the
collective nucleotide contents of the entire microbial community (i.e. the
metagenome), bypassing the need for isolation and lab cultivation of individual
species . Though firstly proposed as early as 1998, the metagenomic method was
easily applicable only after the advent of next-generation sequencing (NGS)
technologies, which have dramatically improved the speed and cost-effectiveness
of DNA sequencing since 2005. Read More>>>>>>>>
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