Human immunodeficiency virus (HIV) infection
is the causative agent of acquired immunodeficiency syndrome, can result in a
wide range of clinical consequences varying from asymptomatic disease to a life threatening opportunistic infections.
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Human Immunodeficiency Virus Infection |
Constant viral replication results in
depletion of peripheral and mucosal CD4 lymphocyte count and function causes
secondary opportunistic infections leading to chronic diarrhea. Gut associated
lymphoid tissues (GALT) is an important location for HIV virus replication and
pathogenesis, targeting mucosal CD4 lymphocytes. It is suggested that the
inflammation in inflammatory bowel disease (IBD) is initiated and propagated by
an aggressive cell-mediated immune response to an unknown antigen in
genetically susceptible host, GALT associated CD4 lymphocyte plays an important
role in pathogenesis of IBD. HIV infection and IBD can coexist in the same
person. Read more>>>>>>>>>>>>>
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