Antimalarial Activity of Ethanolic Leaf Extract of Bauhinia strychnifolia in Mice Infected with Plasmodium berghei

Malaria is an endemic infectious disease that is wide spread in tropical and sub-tropical areas of the world and one of the six most important parasitic disease of human. It is a major public health problem in sub-Saharan Africa, where over 85-90% of all global burden of malaria exists with up to 50% of all outpatient visit in areas with high malaria transmission and 30-50% of all hospital admission are attributed to malaria. 

Each year 1.1 million people die with this disease. Approximately 1 million deaths are in Africa and an estimate 700,000 of them are children. Although an effective vaccine is the best long term control for malaria, current research on vaccine development is still at pre-clinical stage. Therefore, the strategy for malaria mainly focuses on antimalarial drugs capable of reducing or eliminating parasites. However, antimalarial drug resistant Plasmodium species and the emergence of insecticide resistant Anopheles mosquitoes cause not only the spread of malaria to new areas but also its re-emergence in areas where it had previously been eradicated. Read more>>>>>>>>>