Wednesday, 3 May 2017

The Effect of Intravenous Vancomycin in the Reduction of the Incidence of Clostridium difficile Colitis

Pseudomembranous Colitis is a gastrointestinal tract infection caused by the bacteria Clostridium difficile(C. difficile). Clostridium difficile is frequently found in the normal colon, but pathologic overgrowth of C. difficile often occurs following destruction of the normal intestinal flora by antibiotics. 

Clostridium difficile ColitisThis massive overpopulation of C. difficile can result in conditions ranging from mildly debilitating antibiotic associated diarrhoea to life-threatening toxic mega-colon. A large multihospital study of over 10,000 patients found that the adjusted mean cost and length of stay of patients with Clostridium difficile infections was nearly double that of matched control patients ($55,769 vs $28,609; 21.1 vs 10.0 days). Another recent study calculated that a hospital with 4.1 cases of C. difficile infection per 100,000 patient discharges would incur a cost of greater than or equal to $3.2 million dollars. Read more>>>>>>>>>>>>

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